ICCVAM Workshop Series on Best Practices for Regulatory Safety Testing January 20, 2011: Assessing the Potential for Chemically Induced Allergic Contact Dermatitis
نویسندگان
چکیده
2 Plasmacytoid Dendritic Cell-Based Assay as an In Vitro Alternative Assay for Chemical Allergenicity Screening
منابع مشابه
Safety Testing: Moving Toward Alternative Methods
Protection of workers and consumers demands that safety testing accurately detects chemicals and products that can cause injury or disease. Chemicals make our lives more comfortable, but accidental and improper exposures to chemical substances continue to have a significant public health impact. According to the Institute of Medicine (2004), more than 4 million poisonings occur annually in the ...
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Allergic contact dermatitis is an immune-mediated antigen-specific skin reaction to an allergenic chemical that corresponds to a delayed-type hypersensitivity response (type IV reaction). Allergic contact dermatitis should be suspected when skin lesions are localized to the site of previous applications of the culprit drug. Lesions appear after re-exposure in susceptible persons, with delayed o...
متن کاملComparison of patch testing results between job related and non job related allergic contact dermatitis in Iran
Background: Job-related allergic contact dermatitis (ACD) mayprolong the disease duration, increase disabilities, and decreasethe patient’s quality of life. The aim of this study was to determinecommon allergens causing ACD, investigating certain featuresof the disease and evaluating its relation to the patients’ jobs.Method: In this cross-sectional study, relevant data was obtainedfrom patch t...
متن کاملAn 8-year retrospective review of patch testing with rubber allergens: the Mayo Clinic experience.
BACKGROUND Allergic contact dermatitis from rubber chemicals is increasingly recognized. OBJECTIVE To review the results of patch testing with rubber allergens from January 1, 2000, through December 31, 2007. METHODS Patients who underwent patch testing with a specialized series of rubber allergens were identified. RESULTS In total, 773 patients (64.2% female; mean age, 48.6 years) were p...
متن کاملPatch test results in patients with suspected allergic contact dermatitis: a study from Mashhad, Iran and a review of literature
Background: The standard patch test is known as the most reliable test to identify and confirm causative agents of allergic contact dermatitis (ACD). Previous studies have shown that the prevalence of specific allergens varies by geographic area. The results of patch test in patients visiting our dermatology clinics with suspected ACD were prospectively investigated and compared with those repo...
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تاریخ انتشار 2011